Intrahepatic cholangiocarcinoma is a rare type of cancer that originates in the bile ducts inside the liver. It is a highly aggressive and difficult to treat cancer with a poor prognosis. Research in this area focuses on understanding the molecular mechanisms underlying the development and progression of intrahepatic cholangiocarcinoma, identifying potential biomarkers for early detection, and developing more effective treatment strategies, such as targeted therapies and immunotherapy. Additionally, studies are also investigating ways to improve the diagnosis and staging of intrahepatic cholangiocarcinoma to guide personalized treatment approaches and improve patient outcomes.